An all-purpose bathroom spray handles toothpaste splatter and the odd dusty shelf. It does very little against the grime that actually makes a bathroom look tired: the cloudy film on the shower glass, the chalky ring that hard water leaves behind, the black creeping along the caulk and the grout lines that drifted from white to beige years ago.
Each of those problems wants a different tool. Below, every pick is matched to the specific mess it is built for, so you can grab the one or two that fit your bathroom instead of buying a whole cabinet of bottles.
Wet & Forget Shower Cleaner

The problem: soap scum builds up faster than you are willing to scrub it off.
This bleach-free spray is designed for the person who would rather never kneel in a bathtub again. Mist the walls, the door and the floor, leave it to work, then rinse it away the next day. Buyers who use it this way say they have stopped scrubbing entirely; one sprays the whole shower, lets it sit anywhere from an hour to overnight depending on how long it has been, and simply rinses.
If your shower is already in rough shape, run a few applications back to back first, then drop to once a week to keep the buildup from returning. It comes in two scents and two sizes.
Good to know: the floor can feel a little slick afterward, so give it a quick wipe with a washcloth before you step in.
Rain-X Shower Door Cleaner

The problem: you can no longer see through your glass shower door.
Clear glass shows every water spot, and soap residue turns it milky in a matter of weeks. This cleaner is aimed squarely at that haze. The method buyers describe is simple: spread a small amount over the glass with a soft scrubbing pad, work it in circles, then rinse with plain water. A little product covers a lot of door, and the finish people report is streak-free and smear-free, which is the part that usually goes wrong with glass.
Best for: frameless or framed glass doors that look permanently fogged.
Bioclean Hard Water Stain Remover

The problem: mineral deposits that laugh at regular cleaners.
If you live with hard water, you already know the chalky white crust on the shower head and the rusty ring in the toilet. This remover takes on calcium, rust and soap scum with a bit of scrubbing and leaves no streaks. It works on glass doors, nozzles and shower heads, and buyers have also used it on porcelain sinks and brushed nickel faucets.
One reviewer on hard well water had tried a long list of toilet bowl cleaners with no luck before this one finally lifted the brown ring, applied with a blue scrubbing pad. Another plus mentioned: no harsh chemical smell. Three sizes are available.
Kaboom Foaming Mold & Mildew Stain Remover

The problem: dark mildew spots across the tile, especially up high.
Liquid sprays run straight down the wall before they can do much. This bleach-based formula comes out as a thick foam that stays put on vertical tile, so it can actually sit on the stain. Spray, walk away for a short while, then wipe. One buyer with a white tile shower says it replaced hours of scrubbing with a bleach cleaner and a brush, and the tile came out white without any elbow grease.
Good to know: since it contains bleach, keep a window open or the fan running, and keep it away from colored towels and bath mats.
Grout-Eez Super Heavy-Duty Grout Cleaner

The problem: grout that has gone gray, brown or worse.
Grout is porous, so years of dirt settle in rather than on top. This professional-strength cleaner is made to pull that grime back out of floors, countertops and shower tile. A reviewer who had tried store products, homemade mixes and every online trick on the grout beside her stove saw a clear difference after a three-minute spot test, then finished the job with a couple of five-minute rounds.
The smell is noticeable up close, so open a window before you start.
Mold and Mildew Removal Gel

The problem: black caulk around the tub that looks like it needs replacing.
Before you cut out every bead of caulk and start over, try this gel. You lay it along the stained line, leave it for a few hours and wipe it off, no scrubbing involved. Because it is a gel, it stays on the seam instead of sliding into the drain. One buyer whose caulking had turned completely black says a single application brought it back to bright white and saved what would have been hours of re-caulking.
Best for: tub edges, sink seams and the corners of shower pans.
PUFTEM Cordless Electric Spin Scrubber

The problem: your wrists give out before the tub does.
Every cleaner above works better with a little agitation, and this handheld scrubber supplies it so you do not have to. It has two speeds, a battery level display and charges over USB-C, with roughly three hours of run time per charge. A set of swappable brush heads covers flat tile, corners, the sink and even jobs outside the bathroom like the stovetop. Buyers call it lightweight and easy to swap heads on, and one notes it is waterproof enough to use in the shower without worry.
Where to Start
Work from the top down. Tackle mildew and hard water first, since they need the longest dwell time, then the glass, then the grout and caulk at floor level. Once everything is back to clean, a weekly no-scrub spray keeps you from having to repeat the whole project next season.